Pheniramine maleate USP/EP/BP/JP/IP

CAS No. 132-20-7

US DMF 23512

CDMF Y20190000541

CEP RO-CEP 2015-030-Rev 00

EDMF Available


Pheniramine Maleate is the maleate salt form of pheniramine, an alkylamine derivative with anti-histaminic and vasodilatory properties. Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP (cGMP) levels, thereby inhibiting constriction of smooth muscle tissue, and decreased capillary permeability and histamine-activated allergic reactions.

Our Brochure